IMPRINT: Design and Development of Bioresorbable Drug Eluting Coronary Stent

Simulated and manufactured BVS from a bioploymer at IITD

People are getting aware that cardiac diseases are the major killer in India. Angioplasty also known, as Percutaneous Coronary Intervention (PCI) has become an established procedure in treating Coronary Artery Disease (CAD) due to atherosclerosis, which has emerged as a major social epidemic in India in the last three decades. Stenting the plaque artery is the most efficient solution for CAD as a minimally invasive surgical technique.

"As compared to bare metal or drug eluting metallic stents, the future technology is a fully Bioresorbable Vascular Stent (BVS). They can be made up of either biopolymers or biodegradable metals that are fully resorbable inside an artery and leave no permanent implant or any material trace behind after positive remodeling of the lumen" says Prof Naresh Bhatnagar, the principal investigator of the project.

Major research work in case of BVS is to improve the mechanical properties and make it comparable to what an artery or a plaque wants. In this project, apart from design, the technology of manufacturing the BVS will be evolved and improved by using patented processing of medical grade polymer tubing and laser machining of patented stent design developed at IIT Delhi, leading to animal trials and on being successful the First in Man (FIM) trials.